The use of antibiotics in some cases of appendicitis may be effective enough to prevent surgery. A study followed 256 patients for five years after they had been administered antibiotics for uncomplicated appendicitis. That is, patients whose appendix had not ruptured, there was no low white blood count and there was no fecal blockage. The results which were published in JAMA showed 60% of the patients never needed surgery. 70 needed surgery in one year but did not have any life threatening outcomes because of the delay. Of those the decision to operate was made by the physician. It should be discussed with your doctor whether a case of inflammation of the Appendix should first be treated with antibiotics.